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Updated: Mar 22, 2026
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Capture and Release of Viable Circulating Tumor Cells from Blood
Published on: October 28, 2016
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Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating
Hyeun Joong Yoon1,2,3,4, Apoorv Shanker3,5, Yang Wang1,3,4
1Department of Chemical Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109, USA.
Advanced Materials (Deerfield Beach, Fla.)
|April 27, 2016
Abstract:
A highly sensitive microfluidic system to capture circulating tumor cells from whole blood of cancer patients is presented. The device incorporates graphene oxide into a thermoresponsive polymer film to serve as the first step of an antibody functionalization chemistry. By decreasing the temperature, captured cells may be released for subsequent analysis.
