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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Related Experiment Video

Updated: Mar 22, 2026

Reverse Genetics Mediated Recovery of Infectious Murine Norovirus
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Published on: June 24, 2012

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Norovirus in Transplantation.

Michael P Angarone1, Anna Sheahan2, Mini Kamboj2,3

  • 1Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, 645 N Michigan Avenue, Suite 900, Chicago, IL, 60611, USA. m-angarone@northwestern.edu.

Current Infectious Disease Reports
|April 27, 2016
PubMed
Summary

Norovirus (a common cause of diarrhea) poses significant risks for transplant recipients, leading to serious complications. This review covers its epidemiology, diagnosis, and treatment in this vulnerable population.

Keywords:
DiarrheaNorovirusTransplant

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Area of Science:

  • Infectious Diseases
  • Transplantation Medicine
  • Gastroenterology

Background:

  • Noroviruses are a leading cause of gastroenteritis, particularly diarrhea, in immunocompromised individuals.
  • Transplant recipients are susceptible to norovirus infections, which can lead to severe clinical manifestations and complications.
  • The increasing recognition of norovirus-associated morbidity in transplant patients necessitates a comprehensive understanding of the condition.

Purpose of the Study:

  • To review the current knowledge on norovirus infections in transplant recipients.
  • To summarize the epidemiology, clinical spectrum, and complications of norovirus in this population.
  • To discuss diagnostic approaches and therapeutic strategies for norovirus in the transplant setting.

Main Methods:

  • This review synthesizes existing literature on norovirus infection in transplant recipients.
  • Information was gathered from peer-reviewed publications, focusing on epidemiology, clinical outcomes, diagnosis, and treatment.
  • The review provides a summary of current understanding and highlights areas for future research.

Main Results:

  • Norovirus infection is a significant cause of diarrhea and morbidity in transplant recipients.
  • Complications include prolonged illness, malnutrition, organ dysfunction, and chronic viral shedding.
  • The clinical presentation and outcomes can be severe in this immunocompromised group.

Conclusions:

  • Norovirus infection presents a substantial challenge in transplant recipients, associated with significant morbidity.
  • Effective and rapid diagnostic tools and novel therapeutic interventions are crucial.
  • Further research is needed to optimize management and improve outcomes for norovirus-infected transplant patients.