Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

835
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
835
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

4.7K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
4.7K
Nuclear Magnetic Resonance (NMR): Overview01:07

Nuclear Magnetic Resonance (NMR): Overview

7.8K
Nuclear magnetic resonance (NMR) is a phenomenon exhibited by certain nuclei that can absorb characteristic radio frequency radiation under certain conditions. NMR has been extensively applied in molecular spectroscopy and medical diagnostic imaging. In both these applications, the molecule or subject under study is placed in a magnetic field and irradiated with radio frequency energy.
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
7.8K
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

1.4K
The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
1.4K
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

1.1K
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
1.1K
Nuclear Overhauser Enhancement (NOE)01:06

Nuclear Overhauser Enhancement (NOE)

1.6K
Irradiation of a spin-active nucleus causes an increase or decrease in the signal intensity of neighboring nuclei that are not necessarily chemically bonded or involved in J-coupling. This phenomenon, called the nuclear Overhauser enhancement (NOE), results from through-space interactions between the nuclear spins. The NOE effect decreases with increasing internuclear distance and is generally not observed beyond 4 angstroms. In NOE, dipole-dipole interactions between neighboring spin-active...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lateral diffusion of lipids in the DMPG membrane across the anomalous melting regime: effects of NaCl.

Soft matter·2022
Same author

Multiscale lipid membrane dynamics as revealed by neutron spectroscopy.

Progress in lipid research·2022
Same author

A concept of a broadband inverted geometry spectrometer for the Second Target Station at the Spallation Neutron Source.

The Review of scientific instruments·2022
Same author

Dynamics of Emim<sup>+</sup> in [Emim][TFSI]/LiTFSI Solutions as Bulk and under Confinement in a Quasi-liquid Solid Electrolyte.

The journal of physical chemistry. B·2021
Same author

Melittin exerts opposing effects on short- and long-range dynamics in bicontinuous microemulsions.

Journal of colloid and interface science·2021
Same author

Natural Radioactivity of the Crystalline Basement Rocks of the Peloritani Mountains (North-Eastern Sicily, Italy): Measurements and Radiological Hazard.

Radiation protection dosimetry·2020

Related Experiment Video

Updated: Mar 22, 2026

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water
08:48

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water

Published on: April 28, 2022

2.2K

A neutron spectrometer concept implementing RENS for studies in life sciences.

S Magazù1, E Mamontov2

  • 1Department of Mathematics and Informatics Sciences, Physics Sciences and Earth Sciences, University of Messina, Viale F. S. D'Alcontres 31, 98166 Messina, Italy.

Biochimica Et Biophysica Acta. General Subjects
|April 28, 2016
PubMed
Summary
This summary is machine-generated.

The Resolution Elastic Neutron Scattering (RENS) method reveals system dynamics by analyzing scattering intensity. A novel RENS spectrometer concept is proposed for practical implementation and broad applications in life sciences.

Keywords:
Elastic incoherent scatteringLife sciencesNeutron scatteringResolution elastic neutron scattering

More Related Videos

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

4.6K
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

2.9K

Related Experiment Videos

Last Updated: Mar 22, 2026

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water
08:48

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water

Published on: April 28, 2022

2.2K
Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

4.6K
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

2.9K

Area of Science:

  • Neutron scattering physics
  • Materials science
  • Spectroscopy

Background:

  • The Resolution Elastic Neutron Scattering (RENS) method measures elastic scattering intensity.
  • Scans are performed as a function of instrumental energy resolution and temperature.

Purpose of the Study:

  • To propose a novel neutron spectrometer concept for practical implementation of the RENS technique.
  • To enable simultaneous data collection across a wide wavevector range, energy resolution, and temperature.

Main Methods:

  • Utilizing mechanical velocity selection for both incident and scattered neutrons.
  • Employing a rotating collimator-type mechanical device with optimized blade shape.
  • Collecting intensity scans versus energy resolution and temperature.

Main Results:

  • Inflection points in the elastic scattering law indicate intersections between system relaxation time and resolution time.
  • The proposed spectrometer design allows for controlled variation of these parameters.
  • Simulations and experimental data support the RENS method's ability to probe system dynamics.

Conclusions:

  • A RENS spectrometer concept based on velocity selection is presented.
  • This instrument facilitates the practical application of RENS.
  • The spectrometer offers broad applications, particularly in Life Sciences.