Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oral Drug Delivery Systems: Introduction01:23

Oral Drug Delivery Systems: Introduction

204
Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
204
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

2.4K
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
2.4K
Oral Drug Delivery Systems: Delayed-Release Systems01:11

Oral Drug Delivery Systems: Delayed-Release Systems

125
Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...
125
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

204
Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
204
Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

184
Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
184
Routes of Drug Administration: Enteral01:18

Routes of Drug Administration: Enteral

8.2K
Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drug Dissolution Enhancement Using 3D-Printed Silica-Based Oral Films.

The AAPS journal·2025
Same author

Modern trends in the formulation of microparticles for lung delivery using porogens: methods, principles and examples.

Pharmaceutical development and technology·2024
Same author

Preparation and evaluation of spray-dried inhalable microparticles from carrier mixtures.

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti·2024
Same author

Preparation and evaluation of spray-dried inhalable microparticles from carrier mixtures.

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti·2024
Same author

Formulation optimization and evaluation of oromucosal in situ gel loaded with silver nanoparticles prepared by green biosynthesis.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2023
Same author

Optimization of spray-dried porous microparticles preparation for pulmonary delivery.

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti·2023

Related Experiment Video

Updated: Mar 22, 2026

Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals
04:28

Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals

Published on: March 23, 2016

13.3K

[Oral films as perspective dosage form].

Veronika Walicová, Jan Gajdziok

    Ceska a Slovenska Farmacie : Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti
    |April 28, 2016
    PubMed
    Summary

    Oral films, including buccal mucoadhesive and orodispersible types, offer innovative drug delivery. These film-forming polymer formulations provide systemic or local treatment with advantages over conventional dosage forms.

    Area of Science:

    • Pharmaceutical Sciences
    • Drug Delivery Systems

    Background:

    • Oral films, encompassing buccal mucoadhesive and orodispersible films, are advanced formulations for drug administration.
    • These films are designed for local oral mucosa treatment or systemic drug delivery.

    Purpose of the Study:

    • To highlight the innovative nature and advantageous properties of oral film formulations.
    • To discuss the mechanisms of mucoadhesion and rapid dissolution for different oral film types.

    Main Methods:

    • Discussion of film-forming polymers as key excipients.
    • Analysis of mucoadhesive properties for sustained retention.
    • Evaluation of rapid dissolution characteristics for orodispersible films.

    Main Results:

    More Related Videos

    Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals
    04:22

    Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

    Published on: March 30, 2017

    8.1K
    Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
    04:09

    Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

    Published on: December 13, 2024

    1.5K

    Related Experiment Videos

    Last Updated: Mar 22, 2026

    Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals
    04:28

    Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals

    Published on: March 23, 2016

    13.3K
    Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals
    04:22

    Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

    Published on: March 30, 2017

    8.1K
    Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
    04:09

    Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

    Published on: December 13, 2024

    1.5K
  • Oral films offer versatile administration routes within the oral cavity.
  • Mucoadhesive films ensure prolonged contact with the oral mucosa.
  • Orodispersible films facilitate drug absorption without liquid intake.

    • Conclusions:

    • Oral films represent a significant innovation in pharmaceutical dosage forms.
    • These formulations possess the potential to compete with traditional oral drug delivery methods.
    • The development of film-forming polymers is crucial for effective oral film performance.