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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

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Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
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DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
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Diet and Inflammatory Bowel Disease.

Karina Knight-Sepulveda1, Susan Kais1, Rebeca Santaolalla1

  • 1Ms Knight-Sepulveda is a clinical dietitian and Dr Kais is an IBD clinical fellow at the UHealth Crohn's and Colitis Center in the University of Miami Health System in Miami, Florida. Dr Santaolalla is the research laboratory manager at The Micky & Madeleine Arison Family Foundation Crohn's & Colitis Discovery Laboratory at the University of Miami Miller School of Medicine in Miami, Florida. Dr Abreu is a professor of medicine, professor of microbiology and immunology, chief of the Division of Gastroenterology, director of the UHealth Crohn's and Colitis Center, and principal investigator at The Micky & Madeleine Arison Family Foundation Crohn's & Colitis Discovery Laboratory at the University of Miami Miller School of Medicine.

Gastroenterology & Hepatology
|April 28, 2016
PubMed
Summary

Patients with inflammatory bowel disease (IBD) are exploring dietary changes for disease management. This review examines popular diets like low-FODMAP and anti-inflammatory, discussing their supporting evidence for IBD treatment.

Keywords:
Low-FODMAP dietPaleolithic dietanti-inflammatory diethigh-fat dietinflammatory bowel diseaselow-fat dietspecific carbohydrate diet

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Area of Science:

  • Gastroenterology
  • Nutrition Science

Background:

  • Growing patient interest in non-pharmacologic approaches for Inflammatory Bowel Disease (IBD).
  • Diet is a frequently asked question and a key area of focus for IBD management.
  • The role of diet in both the prevention and treatment of IBD is increasingly recognized.

Purpose of the Study:

  • To discuss commonly recommended diets for patients with Inflammatory Bowel Disease (IBD).
  • To review the scientific data supporting the efficacy of these popular diets in IBD management.

Main Methods:

  • Literature review of popular diets recommended for IBD patients.
  • Analysis of available scientific evidence for each discussed diet.
  • Focus on diets including low-fermentable oligosaccharide, disaccharide, monosaccharide, and polyol (FODMAP) diet, Specific Carbohydrate Diet (SCD), anti-inflammatory diet, and Paleolithic diet.

Main Results:

  • Several diets, including low-FODMAP, SCD, anti-inflammatory, and Paleolithic, are popular among IBD patients.
  • There is a general lack of rigorous scientific evidence to definitively establish the best diet for all IBD patients.
  • Evidence supporting specific dietary interventions varies, with some showing promise for symptom management.

Conclusions:

  • Dietary interventions are a significant area of interest for IBD patients seeking alternative management strategies.
  • Further high-quality research is needed to establish evidence-based dietary guidelines for IBD.
  • Current popular diets offer potential benefits, but individualized approaches and continued research are crucial.