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Updated: Mar 22, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Early osteoarthritis of the patellofemoral joint
Elizabeth A Arendt1, Massimo Berruto2, Giuseppe Filardo3
1Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Av. So., Ste. R200, Minneapolis, MN, 55454, USA. arend001@umn.edu.
Abstract:
Patellofemoral joint cartilage lesions are associated with a variety of clinical situations including blunt trauma, lateral patella dislocations, or as a secondary development in the setting of abnormal joint loading. There is a need for more clarity on how to best address these lesions. Most specifically, when is it necessary to surgically treat these lesions of the patella and trochlea and which technique to use? This review will focus on the spectrum of patellofemoral disease/injury and their treatment strategies, with special emphasis on cartilage damage and early osteoarthritis. Chapter sections will review the most common scenarios of cartilage damage in the patellofemoral joint, with an attempt to summarize current treatment, their outcomes, remaining challenges and unanswered questions.
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