Jove
Visualize
Contact Us

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

2.1K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.1K
Skin Cancer01:30

Skin Cancer

6.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.6K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

6.3K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
6.3K
Cancer Vaccines01:30

Cancer Vaccines

1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structural drivers of drug shortages and market withdrawal: a longitudinal analysis of the Romanian pharmaceutical market.

BMC health services research·2026
Same author

Structural Patterns of Antibiotic Shortages: A Cross-National Analysis of Systemic Antibacterials.

Antibiotics (Basel, Switzerland)·2026
Same author

Melissopalynological and Physicochemical Analysis of Selected Honey Samples from Romania, Spain, Malaysia, and New Zealand.

Foods (Basel, Switzerland)·2026
Same author

Full-Arch Oral Rehabilitation in All-on-4 "M" Configuration Using Surgical Guides with Internal Cooling: A Clinical Case Report.

Journal of clinical medicine·2026
Same author

Cell-Based Computational Models of Organoids: A Systematic Review.

Cells·2026
Same author

Toll-like Receptor 7/8 Agonists Exert Antitumor Effect in a Mouse Melanoma Model.

Medicina (Kaunas, Lithuania)·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 22, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

4.2K

Immune based therapy for melanoma.

Robert Ancuceanu1, Monica Neagu

  • 1University of Medicine and Pharmacy "Carol Davila", Bucharest, Faculty of Pharmacy, Bucharest, Romania.

The Indian Journal of Medical Research
|April 29, 2016
PubMed
Summary

Recent advancements in advanced melanoma treatment offer new hope. Several immunotherapies, including ipilimumab and anti-PD1 inhibitors, have been approved, with more therapies in development.

Area of Science:

  • Oncology
  • Immunology
  • Dermatology

Background:

  • Advanced melanoma previously had limited treatment options and a poor prognosis.
  • Recent therapeutic progress has significantly improved outcomes and outlook for patients.

Purpose of the Study:

  • To review recent advancements in the treatment of advanced melanoma.
  • To highlight novel therapeutic agents and their mechanisms of action.

Main Methods:

  • Review of recently authorized therapies for advanced melanoma.
  • Discussion of immunotherapeutic agents such as ipilimumab and anti-PD1 inhibitors.
  • Inclusion of oncolytic immunotherapy (talimogene laherparepvec) and combination strategies.

Main Results:

More Related Videos

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

16.8K
Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
07:36

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

7.9K

Related Experiment Videos

Last Updated: Mar 22, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

4.2K
A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

16.8K
Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
07:36

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

7.9K
  • Seven new medicines have been approved globally for advanced melanoma treatment.
  • Over half of these new therapies leverage the host's immune system.
  • Emerging therapies include anti-CTLA-4, anti-PD1 inhibitors, and oncolytic viruses.

    • Conclusions:

    • Current therapeutic options for advanced melanoma have expanded significantly.
    • Immunotherapy and combination approaches represent the forefront of treatment innovation.
    • Ongoing research into novel molecules and strategies promises further benefits for patients.