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PCSK9 Association With Lipoprotein(a).

Hagai Tavori1, Devon Christian2, Jessica Minnier2

  • 1From the Department of Medicine, Center for Preventive Cardiology, Knight Cardiovascular Institute, Portland, OR (H.T., D.C., D.P., M.D.S., I.G., P.B.D., S.F.); School of Public Health, Oregon Health and Science University, Portland (J.M.); Sulpizio Cardiovascular Center, Vascular Medicine Program, University of California at San Diego, La Jolla (C.Y., S.T.); Inra UMR1280, Université de Nantes, CHU Hôtel-Dieu, Nantes, France (M.C., G.L.); Inserm UMR 1188, Sainte-Clotilde, France (G.L.); Université de la Réunion, Faculté de Médecine, Saint-Denis, France (G.L.); and CHU de la Réunion, Saint-Denis, France (G.L.). fazio@ohsu.edu tavori@ohsu.edu.

Circulation Research
|April 29, 2016
PubMed
Summary

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with Lipoprotein(a) [Lp(a)] particles in humans and mice. This Lp(a)-bound PCSK9 may serve as a novel biomarker for cardiovascular risk assessment.

Keywords:
lipids and lipoprotein metabolismlipoprotein(a)low-density lipoproteinproprotein convertase subtilisin/Kexin type 9

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