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Screening for grades of frailty using electronic health records: where do we go from here?

Kenneth Rockwood1

  • 1Centre for the Health Care of Elderly People, Geriatric Medicine Dalhousie University, Halifax, Nova Scotia, Canada B3H 2E1 Geriatric Medicine, University of Manchester, Manchester, UK.

Age and Ageing
|April 29, 2016
PubMed
Abstract

No abstract available in PubMed .

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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