Related Experiment Video
Updated: Mar 22, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Seeing the Forest Through the Trees: Improving Adherence Alone Will Not Optimize Medication Use
Todd D Sorensen1, Deborah L Pestka2, Amanda R Brummel3
11 Department of Pharmaceutical Care and Health Systems, University of Minnesota, Minneapolis.
Medication adherence measures often overlook patient-centered factors, focusing instead on simple metrics. A comprehensive approach is needed to address the most common medication problems and improve patient health outcomes.
Area of Science:
- Health Services Research
- Medication Management
- Patient-Centered Care
Background:
- Medication adherence is a key focus in healthcare quality measurement.
- Current quality metrics often neglect patient-specific factors like clinical status or social situations.
- Nonadherence can stem from issues beyond simply not taking medication as prescribed.
Purpose of the Study:
- To highlight the limitations of current medication adherence quality measures.
- To advocate for a more comprehensive assessment of medication-related problems.
- To emphasize the importance of patient-centered factors in medication management.
Main Methods:
- Literature review and analysis of current quality metrics for medication adherence.
- Discussion of common medication-related problems beyond nonadherence.
- Conceptual framework for evaluating medication use in patient-centered contexts.
Main Results:
- Current adherence metrics, like proportion of days covered, are insufficient.
- More frequent medication problems include incorrect prescriptions or suboptimal dosing.
- Focusing solely on adherence without considering indication, efficacy, and safety can cause harm.
Conclusions:
- Quality measures must evolve to incorporate patient-centered issues for effective medication management.
- Addressing the full spectrum of medication-related problems is crucial for achieving the Triple Aim of healthcare.
- Leadership and advocacy are needed to broaden the scope of medication quality measurement.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Bioavailability Enhancement: Drug Permeability Enhancement
Drug Dosing: Geriatric Patients
Therapeutic Drug Monitoring: Affecting Factors
Dosage Regimen: Fixed Dose
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...

