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Retinal periphlebitis after hormonal treatment.

T Rock1, Y Dinar, M Romem

  • 1Department of Ophthalmology, Sackler Faculty of Medicine, Tel-Aviv University, Edith Wolfson Medical Center, Holon, Israel.

Annals of Ophthalmology
|February 1, 1989
PubMed
Summary

Hormonal treatments for infertility and contraceptives can cause retinal periphlebitis, leading to vision loss. Prompt corticosteroid treatment can rapidly improve visual acuity in affected individuals.

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Area of Science:

  • Ophthalmology
  • Endocrinology

Background:

  • Hormonal therapies, including those for infertility and contraception, are widely used.
  • Potential ocular side effects of hormonal treatments require thorough investigation.

Observation:

  • Two patients presented with unilateral severe visual acuity decrease, central scotoma, and color vision defects.
  • Fundus examination revealed retinal edema, optic disc hyperemia, venous congestion, and perivenous sheathing with hemorrhages.

Findings:

  • Retinal periphlebitis was diagnosed following hormonal treatment.
  • Fluorescein angiography demonstrated delayed venous filling and late venous staining.
  • Systemic adrenocorticosteroid therapy resulted in rapid visual acuity improvement.

Implications:

  • This highlights a potential link between hormonal treatments and retinal periphlebitis.
  • Early diagnosis and intervention with corticosteroids are crucial for managing visual impairment.
  • Long-term sequelae, such as visual field defects, may persist despite treatment.

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