Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nanofiber based transformative approaches for tendon regenerative engineering: past, present and future.

Nanomedicine (London, England)·2026
Same author

Magnesium phosphate functionalized graphene oxide and PLGA composite matrices with enhanced mechanical and osteogenic properties for bone regeneration.

Regenerative biomaterials·2025
Same author

Osteoinductive low-dose 3D porous calcium phosphate graphene oxide-integrated matrices enhance osteogenesis and mechanical properties.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Graphene Oxide in Bone Regenerative Engineering: Current Challenges and Future Perspectives.

ACS bio & med chem Au·2025
Same author

A novel protocol for the direct isolation of a highly pure and regenerative population of satellite stem cells.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Fat Expansion Not Fat Infiltration of Muscle Post Rotator Cuff Tendon Tears of the Shoulder: Regenerative Engineering Implications.

Regenerative engineering and translational medicine·2025

Related Experiment Video

Updated: Mar 22, 2026

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.6K

Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering.

Ganesh Narayanan1, Varadraj N Vernekar1, Emmanuel L Kuyinu1

  • 1Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA.

Advanced Drug Delivery Reviews
|April 30, 2016
PubMed
Summary
This summary is machine-generated.

Regenerative engineering uses advanced biomaterials like poly (lactic acid) (PLA) scaffolds to repair tissues. This review highlights PLA

Keywords:
BoneCartillageGrowth factorsLigamentMeniscus regenerationPoly (lactic acid)Regenerative EngineeringSmall molecules

More Related Videos

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
10:32

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Published on: March 26, 2015

10.9K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.2K

Related Experiment Videos

Last Updated: Mar 22, 2026

Novel Process for 3D Printing Decellularized Matrices
08:14

Novel Process for 3D Printing Decellularized Matrices

Published on: January 7, 2019

7.6K
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
10:32

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Published on: March 26, 2015

10.9K
A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

Published on: October 17, 2016

9.2K

Area of Science:

  • Regenerative engineering
  • Biomaterials science
  • Tissue engineering

Background:

  • Regenerative engineering integrates multiple disciplines to restore complex tissues.
  • Scaffolds are crucial for providing mechanical support and controlling cellular environments.
  • Poly (lactic acid) (PLA)-based biomaterials are versatile and widely used in orthopaedics.

Purpose of the Study:

  • To review recent advancements in poly (lactic acid) (PLA)-based biomaterials for regenerative engineering.
  • To discuss the processability and applications of PLA in clinical and research settings.
  • To focus on applications in bone, ligament, meniscus, and cartilage regeneration.

Main Methods:

  • Literature review of recent developments in PLA-based biomaterials.
  • Analysis of PLA processability for scaffold fabrication.
  • Examination of current applications in orthopaedic regenerative engineering.

Main Results:

  • PLA offers excellent versatility in fabrication, biodegradability, and biocompatibility.
  • Recent developments have improved PLA processability for complex scaffold designs.
  • PLA scaffolds show significant promise in regenerating bone, ligament, meniscus, and cartilage.

Conclusions:

  • Poly (lactic acid) (PLA) is a leading biomaterial for orthopaedic regenerative engineering.
  • Continued innovation in PLA processing will expand its clinical applications.
  • PLA-based scaffolds are key to advancing tissue regeneration for various orthopaedic needs.