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Updated: Mar 22, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Familial superior mesenteric artery syndrome
Ana Raquel Martins1, José Filipe Cunha2, Joana Patrício3
1Department of Surgery, Hospital do Espirito Santo de Evora EPE, Evora, Portugal.
Superior mesenteric artery syndrome (SMAS) is a rare condition caused by duodenal compression. This case highlights a successful surgical intervention for a young woman with chronic symptoms.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Medical Imaging
Background:
- Superior mesenteric artery syndrome (SMAS) affects 0.1-0.3% of the population, characterized by duodenal compression due to a narrow aortomesenteric angle.
- It predominantly impacts females under 30 and can be congenital or acquired, with a rare familial form reported.
Observation:
- A 20-year-old female presented with a decade of recurrent epigastric discomfort and vomiting, suggestive of SMAS.
- Diagnostic workup included digestive endoscopy, upper gastrointestinal transit imaging, and abdominal MRI, confirming the diagnosis.
Findings:
- The patient underwent surgical intervention after 17 days of parenteral nutrition.
- Postoperative recovery was uneventful, with discharge occurring 8 days after surgery.
Implications:
- This case underscores the importance of considering SMAS in young patients with chronic gastrointestinal symptoms.
- Effective diagnosis and surgical management can lead to positive patient outcomes.
- Further research into the familial and acquired etiologies of SMAS may improve early detection and treatment strategies.
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