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Published on: January 21, 2020
Emergency management for congenital tracheal stenosis with endoluminal stenting in pediatric intensive care units
Xuan Xu1, Hui Ding2, Xicheng Liu3
1Bayi Children's Hospital, Affiliated to Beijing Military General Hospital, Beijing, China.
Insights
Self-expanding intraluminal stents effectively managed congenital tracheal stenosis (CTS) in infants, improving respiratory obstruction and enabling successful extubation. This airway stenting approach offers a valuable therapeutic option for infants with CTS.
Area of Science:
- Pediatric Pulmonology
- Interventional Bronchoscopy
- Medical Device Technology
Background:
- Congenital tracheal stenosis (CTS) presents a significant challenge in infant respiratory care.
- Limited effective treatment options exist for severe CTS, often requiring complex surgical interventions.
Purpose of the Study:
- To evaluate the safety and efficacy of self-expanding intraluminal stents for managing congenital tracheal stenosis in infants.
- To share clinical experience and outcomes of airway stenting in a pediatric intensive care unit (PICU) setting.
Main Methods:
- A retrospective study of 31 infants diagnosed with CTS between January 2010 and August 2012.
- Bronchoscopic placement of self-expanding intraluminal stents in infants requiring respiratory support.
- Assessment of immediate respiratory improvement, complications, stent functionality, and long-term outcomes.
Main Results:
- All 31 infants experienced immediate improvement in respiratory obstruction post-stenting, facilitating weaning from mechanical ventilation and extubation.
- No immediate stent-related airway complications occurred; granulation tissue in 9.7% of cases was managed successfully with cryotherapy.
- Stents remained functional in 29 infants up to 24 months, with successful retrieval in seven cases and replacement needed in three.
Conclusions:
- Airway stenting with self-expanding intraluminal stents is a viable and effective therapeutic option for infants with congenital tracheal stenosis.
- This minimally invasive approach can significantly improve respiratory function and reduce the need for more invasive procedures in infants with CTS.
Objective:
The objective of this study was to share our experience in the management of congenital tracheal stenosis (CTS) using self-expanding intraluminal stents in infants.
Methods:
From January 2010 to August 2012, 31 infants with CTS treated using stents by bronchoscope in pediatric intensive care units (PICUs) were recruited for this study.
Results:
Among the 31 patients, 17 were male and 14 were female with their ages ranging from 55 days to 22 months. CTS was associated with congenital heart disease (CHD) in 22 patients. There were no immediate stent-related airway complications. A significant and immediate improvement of respiratory obstruction following stent placement in all 31 patients led to successful weaning from the breathing machine and extubation. Granulation tissue formation as a complication was observed in three (9.7%) patients, but all were successfully managed using cryotherapy. During follow up (up to 24 months), stents in 29 infants remained functional. In seven cases, stents were retrieved under bronchoscope (the same day to 10 months), and three cases required stent replacement (each of the three cases had the stent replaced three times). Nine infants died after stenting due to other causes and two infants abandoned treatment.
Conclusion:
Airway stenting may provide an important therapeutic option in infants with CTS.
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