Anaerobic training in hypoxia: A new approach to stimulate the rating of effort perception

This study compared subjective effort perception with objective physiological measures during high-intensive intermittent exercise performed in normoxia, moderate hypoxia (FiO2: 16.5%) and severe hypoxia (FiO2: 13.5%). Sixteen physically active subjects performed an equal training session on three different days. Training consisted of 6 "all-out" series of continuous jumps lasting for 15s each. Average power output during the jumps was similar in all three conditions (~3200W). Greater hypoxemia was observed in hypoxia as compared to normoxia. Likewise, a significantly higher value in perceived effort was observed after hypoxia training as compared to normoxia training (p<0.05). Whereas blood lactate concentrations immediately after training were not different between normoxia and hypoxia, creatine kinase increased in moderate (p=0.02) and severe (p<0.01) hypoxia compared to normoxia 24h after the training. Perceived fatigue was also significantly elevated 24h after hypoxic exercise only. Heart rate variability pre and 24h after exercise showed a tendency to sympathetic predominance in severe hypoxia as compared to moderate hypoxia and normoxia. In conclusion, a single session of anaerobic exercise can be executed at the same intensity in moderate/severe hypoxia as in normoxia. This type of hypoxic training may be considered as a method potentially to improve the ability tolerating discomfort and consequently also exercise performance.