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Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

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Extended lymph node dissection in robotic radical prostatectomy: Current status.

Sameer Chopra¹, Mehrdad Alemozaffar¹, Inderbir Gill¹

¹Department of Urology, Catherine and Joseph Aresty USC, Institute of Urology, Center for Advanced Robotic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Indian Journal of Urology : IJU : Journal of the Urological Society of India

|April 30, 2016

Summary

This summary is machine-generated.

Radical prostatectomy with extended pelvic lymph node dissection improves survival for prostate cancer patients with lymph node involvement. Further research is needed to refine surgical techniques and post-operative care.

Keywords:

Lymph node-positive metastasis pelvic lymph node dissection prostate cancer radical prostatectomy

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Area of Science:

Urologic Oncology
Surgical Oncology

Background:

The precise role and extent of extended pelvic lymph node dissection (ePLND) in radical prostatectomy (RP) for prostate cancer are not fully established.
Current treatment paradigms for lymph node-positive prostate cancer are being re-evaluated.

Purpose of the Study:

To review the literature on treatment regimens and outcomes for prostate cancer patients undergoing RP with ePLND.
To assess the impact of ePLND on survival and staging in prostate cancer.

Main Methods:

A comprehensive literature search of PubMed was conducted.
Studies published between 1999 and 2013 reporting on RP and ePLND for prostate cancer were included.

Main Results:

Radical prostatectomy (RP) demonstrates potential to improve progression-free and overall survival in lymph node-positive prostate cancer.
Extended pelvic lymph node dissection (ePLND) up to the common iliac arteries is recommended for intermediate- and high-risk patients to enhance nodal staging.
ePLND may alter the surgical approach for patients with limited lymph node tumor infiltration.

Conclusions:

Literature suggests that radical prostatectomy (RP) combined with extended pelvic lymph node dissection (ePLND) enhances survival in prostate cancer patients with lymph node-positive disease.
Further research is necessary to optimize surgical techniques and postoperative management for improved outcomes in prostate cancer with lymph node involvement.