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Related Experiment Videos

Indices of renal function: reference values in normal horses.

D J Edwards1, M A Brownlow, D R Hutchins

  • 1Department of Veterinary Clinical Studies, University of Sydney Rural Veterinary Centre, Camden, New South Wales.

Australian Veterinary Journal
|February 1, 1989
PubMed
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Establishing reference values for equine renal function revealed that while blood values are consistent, urine composition varies widely in healthy horses. This highlights the kidney's adaptability to environmental and management factors.

Area of Science:

  • Veterinary Medicine
  • Equine Physiology
  • Renal Function Studies

Background:

  • Clinical evaluation of renal function in horses relies on various blood and urine parameters.
  • Previous studies established normal ranges for equine blood biochemical values.
  • Understanding urine concentration and electrolyte excretion variability is crucial for accurate renal assessment.

Purpose of the Study:

  • To establish reference values for renal function parameters in normal adult horses.
  • To compare blood and urine biochemical profiles in healthy horses undergoing routine investigations.
  • To investigate the variability of urine concentration and electrolyte excretion in response to environmental and management factors.

Main Methods:

  • Simultaneous collection of urine and blood samples from normal adult horses.

Related Experiment Videos

  • Analysis of blood biochemical values and urine parameters, including concentration and electrolytes.
  • Calculation of percent creatinine clearance ratios for specific electrolytes like potassium.

    • Main Results:

    • Equine blood biochemical values aligned with previously reported findings, showing well-defined normal ranges.
    • Urine concentration and electrolyte excretion parameters exhibited wide variations in healthy horses.
    • Percent creatinine clearance ratios for potassium were found to be lower than previously reported values for normal horses.

    Conclusions:

    • The healthy equine kidney demonstrates significant adaptability in urine composition based on environment and management.
    • Interpretation of urine concentration and electrolyte excretion requires consideration of a broad range of normal values.
    • Management conditions are a critical factor in the rational interpretation of equine renal function tests.