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All-optical optoacoustic microscope based on wideband pulse interferometry.

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    This study introduces an all-optical optoacoustic microscope using a pi-phase-shifted fiber Bragg grating (π-FBG) sensor. This novel approach enhances sensitivity and imaging capabilities for biological specimens.

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    Area of Science:

    • Biomedical Optics
    • Microscopy
    • Acoustic Imaging

    Background:

    • Hybrid optical and optoacoustic microscopy offers enhanced tissue contrast.
    • Current hybrid systems are limited by integrating optical objectives with ultrasound detection.
    • Developing novel ultrasound sensors is crucial for advancing optoacoustic microscopy.

    Purpose of the Study:

    • To present an all-optical optoacoustic microscope utilizing a pi-phase-shifted fiber Bragg grating (π-FBG) sensor.
    • To demonstrate the high sensitivity and imaging performance of the π-FBG sensor.
    • To showcase the first optoacoustic images of biological specimens acquired with this new technology.

    Main Methods:

    • Development of an all-optical optoacoustic microscope system.
    • Integration of a pi-phase-shifted fiber Bragg grating (π-FBG) as an ultrasound detector.
    • Utilizing coherence-restored pulsed interferometry (CRPI) for sensor interrogation.
    • Characterization of the ultrasound detector's spectral bandwidth and imaging performance.

    Main Results:

    • The π-FBG sensor achieved higher sensitivity compared to piezoelectric transducers of similar size.
    • The system successfully acquired the first optoacoustic images of biological specimens using π-FBG sensors.
    • The spectral bandwidth of the ultrasound detector was characterized.

    Conclusions:

    • The developed all-optical optoacoustic microscope with π-FBG sensors offers a promising alternative to existing hybrid systems.
    • The π-FBG sensor provides an ultra-small footprint and enhanced sensitivity for optoacoustic imaging.
    • This technology holds potential for various applications in biological and medical imaging.