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Initial 3D Cell Cluster Control in a Hybrid Gel Cube Device for Repeatable Pattern Formations
Published on: March 21, 2019
Tissue in Cube: In Vitro 3D Culturing Platform with Hybrid Gel Cubes for Multidirectional Observations
Masaya Hagiwara1, Tomohiro Kawahara2, Rina Nobata1
1Nanoscience and Nanotechnology Research Center, Research Organization for the 21st Century, Osaka Prefecture University, 1-2 Gakuen-cho, Naka-ku Sakai-shi, Osaka, 599-8570, Japan.
Abstract:
An in vitro 3D culturing platform enabling multidirectional observations of 3D biosamples is presented. The 3D structure of biosamples can be recognized without fluorescence. The cubic platform employs two types of hydrogels that are compatible with conventional culture dishes or well plates, facilitating growth in culture, ease of handling, and viewing at multiple angles.
