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Updated: Mar 22, 2026

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Published on: January 12, 2019
Family Functioning and the Well-Being of Children With Chronic Conditions: A Meta-Analysis
Jennifer Leeman1, Jamie L Crandell2, Anna Lee3
1Assistant Professor, School of Nursing, University of North Carolina, 5004 Carrington Hall, CB 7460, Chapel Hill, NC, 27599-7460.
Insights
Family functioning significantly impacts child well-being across various chronic conditions. Cohesion and low conflict within families are strongly linked to better child psychological health and fewer behavioral issues.
Area of Science:
- Pediatric Health
- Family Psychology
- Systematic Review & Meta-Analysis
Background:
- Child well-being is intrinsically linked to family functioning, particularly for those with chronic health conditions.
- Previous research has often focused on single conditions, limiting broader insights.
- Synthesizing findings across diverse chronic conditions is crucial for comprehensive understanding.
Purpose of the Study:
- To systematically review and meta-analyze the relationship between family functioning and child well-being across a spectrum of chronic physical conditions.
- To identify specific family functioning dimensions that most influence child outcomes.
Main Methods:
- A meta-analysis was conducted on 53 studies from a larger systematic review (2000-2014).
- Studies analyzed family functioning using established measures (e.g., FACES, FES, FRI, FAD).
- Meta-analyses included 37 comparable studies, focusing on conditions like diabetes, cancer, sickle cell disease, and asthma.
Main Results:
- Significant correlations were found between seven of nine family functioning dimensions and children's psychological health.
- Family functioning dimensions also correlated with children's problem behaviors, social competence, quality of life, adherence, and physical health.
- Family cohesion and low conflict demonstrated the strongest associations with child outcomes.
Conclusions:
- Specific family variables, notably cohesion and conflict, are critical targets for intervention development.
- Understanding these family dynamics is key to improving well-being for children with chronic conditions.
- This synthesis provides a foundation for evidence-based interventions across multiple pediatric chronic conditions.
Abstract:
For children with chronic conditions, well-being is closely related to how well their families function. Most prior research syntheses on family functioning and child well-being have focused on children with a single condition, thereby limiting the potential to aggregate and build on what is known across conditions. To address this challenge, research reports were reviewed and meta-analyses conducted of findings on the relationship between family functioning and child well-being across a range of chronic physical conditions. The sample was derived from a larger systematic review study that included 1,028 reports published between January 1, 2000 and March 31, 2014. The current review includes 53 studies in which a relationship between family functioning and child well-being was analyzed using one of four family measures: Family Adaptability and Cohesion Evaluation Scales, Family Environment Scale, Family Relationship Index, or Family Assessment Device. Most studies were cross-sectional and observational (n = 43, 81%). The most frequently studied conditions were diabetes, cancer, sickle cell disease, and asthma. In 37 studies, findings were sufficiently comparable to conduct meta-analyses. Significant correlations were identified between children's psychological health and seven of nine dimensions of family functioning. Significant correlations also were found between dimensions of family functioning and children's problem behaviors, social competence, quality of life, and, to a lesser extent, adherence and physical health. Of the family dimensions, cohesion and conflict were associated most strongly with child outcomes. Understanding the specific family variables, such as conflict, linked to varied child outcomes is key for intervention development. © 2016 Wiley Periodicals, Inc.
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