Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infection and premature labor.

W J Ledger1

  • 1Department of Obstetrics and Gynecology, Cornell University Medical College, New York, NY.

American Journal of Perinatology
|April 1, 1989
PubMed
Summary

Infection may cause premature labor, suggesting antibiotics could treat the cause. Preliminary studies show antibiotic interventions are encouraging for both symptomatic and asymptomatic women, potentially revolutionizing preterm labor treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bacterial vaginosis: a critical analysis of current knowledge.

BJOG : an international journal of obstetrics and gynaecology·2016
Same author

Differential expression of lactic acid isomers, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-8 in vaginal fluid from women with vaginal disorders.

BJOG : an international journal of obstetrics and gynaecology·2014
Same author

Autophagy and female genital tract infections: new insights and research directions.

BJOG : an international journal of obstetrics and gynaecology·2014
Same author

Are we using too many antibiotics during pregnancy?

BJOG : an international journal of obstetrics and gynaecology·2013
Same author

Relationship between clinical diagnosis of recurrent vulvovaginal candidiasis and detection of Candida species by culture and polymerase chain reaction.

Archives of gynecology and obstetrics·2008
Same author

Chlamydia trachomatis infection, Fallopian tube damage and a mannose-binding lectin codon 54 gene polymorphism.

Human reproduction (Oxford, England)·2007

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Neonatal Health

Background:

  • Strong evidence suggests infection contributes to premature labor.
  • Historical data from the preantibiotic era supports the link between infections like pyelonephritis and pneumonia with preterm labor.
  • Vaginal and amniotic fluid studies reveal specific microbiologic profiles in women experiencing preterm labor.

Purpose of the Study:

  • To explore the hypothesis that infection is a causative factor in premature labor.
  • To evaluate the potential of antibiotics as a causal treatment for preterm labor, contrasting with symptomatic treatments.
  • To review preliminary findings on antibiotic interventions in preterm labor.

Main Methods:

  • Review of historical data from the preantibiotic era.
  • Analysis of vaginal bacterial colonization and amniotic fluid studies.
  • Examination of preliminary reports on antibiotic interventions.

Main Results:

  • Historical data indicates a correlation between infections and premature labor.
  • Microbiologic studies identify specific infectious agents in a subset of preterm labor cases.
  • Preliminary antibiotic interventions show encouraging results in both symptomatic and asymptomatic women.

Conclusions:

  • Infection is a significant factor in premature labor.
  • Antibiotic treatment offers a potential causal therapy for infection-related preterm labor.
  • Further research into antibiotic interventions may herald a new era in managing preterm labor.

Related Experiment Videos