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Patient-reported barriers to osteoporosis therapy
Brianna R Lindsay1, Temitope Olufade2, Jennifer Bauer3
1Center for Observational and Real-World Evidence, Merck & Co. Inc., Kenilworth, NJ, USA. Brianna_lindsay@merck.com.
Archives of Osteoporosis
|May 1, 2016
Summary
Patients often avoid or stop osteoporosis treatment due to fear of side effects or preference for alternative therapies. Experiencing side effects significantly reduces willingness to restart osteoporosis medication.
Area of Science:
- Gerontology
- Pharmacology
- Public Health
Background:
- Osteoporosis treatment adherence is a significant challenge in patient care.
- Patient-reported reasons for non-treatment and discontinuation are crucial for improving therapeutic strategies.
Purpose of the Study:
- To investigate patient-identified barriers to initiating osteoporosis therapy.
- To explore patient-identified reasons for discontinuing osteoporosis treatment.
Main Methods:
- An internet-based survey was conducted among postmenopausal women in the USA diagnosed with osteoporosis.
- Respondents were recruited via consumer research panels, with nominal compensation provided.
Main Results:
- Key reasons for non-treatment included preference for alternative treatments (57.5%) and fear of side effects (43.9%).
- Discontinuation reasons cited physician direction (41.2%), long-term safety concerns (30.3%), and experienced side effects (29.8%).
- Patients unwilling to restart therapy reported higher rates of side effects (44.2%) compared to those willing (20.5%).
Conclusions:
- Patient-reported barriers to osteoporosis treatment include preference for alternative therapies and fear of side effects.
- Side effects are a primary driver for treatment discontinuation and negatively impact willingness to resume therapy.
- Addressing patient concerns about side effects and alternative treatments is vital for improving osteoporosis management.
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