Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modeling of light propagation in the human neck for diagnoses of thyroid cancers by diffuse optical tomography.

International journal for numerical methods in biomedical engineering·2016

Same author

Measurement of the branching fraction B(Λc+ → pK-π+).

Physical review letters·2014

Same author

Observation of D0-D0 mixing in e+e- collisions.

Physical review letters·2014

Same author

Measurement of the τ-lepton lifetime at Belle.

Physical review letters·2014

Same author

Search for bottomonium states in exclusive radiative Υ(2S) decays.

Physical review letters·2013

Same author

Precision measurement of charged pion and kaon differential cross sections in e+ e- annihilation at sqrt[s]=10.52 GeV.

Physical review letters·2013

Search research articles

Related Experiment Video

Updated: Mar 22, 2026

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology

Published on: March 22, 2024

Hemodynamic signals in fNIRS.

¹Institute for Medical Photonics Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Progress in Brain Research

|May 1, 2016

Summary

This summary is machine-generated.

Near-infrared spectroscopy (NIRS) measures cerebral hemoglobin to detect brain activity, but extracerebral tissue signals can interfere. Distinguishing these signals is key to advancing functional NIRS (fNIRS) for better neuroimaging.

Keywords:

DOT Deoxy-Hb EEG Extracerebral tissues NIRS Oxy-Hb Spontaneous fluctuations fMRI t-Hb

More Related Videos

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Published on: December 5, 2014

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Published on: December 3, 2020

Related Experiment Videos

Last Updated: Mar 22, 2026

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology

Published on: March 22, 2024

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks

Published on: December 5, 2014

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Published on: December 3, 2020

Area of Science:

Neuroscience
Biomedical Engineering
Medical Physics

Background:

Near-infrared spectroscopy (NIRS) monitors tissue oxygenation and is used in functional NIRS (fNIRS) for neuroimaging.
fNIRS detects cerebral activation by measuring hemoglobin (Hb) changes.
The precise correlation between NIRS signals and neural activity is not fully understood due to extracerebral signal contamination.

Purpose of the Study:

To review the basic theory of NIRS and its application in fNIRS.
To explore correlations between NIRS signals and fMRI/neural activities.
To discuss methods for distinguishing cerebral from extracerebral NIRS signals.

Main Methods:

Review of existing literature on NIRS and fNIRS.
Analysis of signal contamination from extracerebral tissues.
Discussion of approaches to isolate cerebral signals.

Main Results:

NIRS signals are influenced by extracerebral tissue, complicating the interpretation of cerebral activity.
Various methods are being investigated to separate cerebral and extracerebral signals.
Selective measurement of cerebral Hb is crucial for fNIRS advancement.

Conclusions:

Distinguishing between cerebral and extracerebral signals is essential for the accurate application of fNIRS.
Further research into signal processing and measurement techniques will enhance fNIRS capabilities.
Selective cerebral Hb measurements promise to evolve fNIRS as a neuroimaging tool.