Related Experiment Video
Updated: Mar 21, 2026
An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Comparison of Oral Function: Free Anterolateral Thigh Perforator Flaps Versus Vascularized Free Forearm Flap for
Yuan Yuan1, Peipei Zhang2, Wei He3
1Researcher, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Purpose:
This study evaluated oral function in patients with tongue cancer who underwent immediate free flap reconstruction surgery. In addition, the efficacy of the anterolateral thigh perforator free flap (ALTFF) and the radial free forearm flap (RFFF) for reconstruction was compared in patients with glossectomy.
Materials And Methods:
Sixty-seven patients undergoing complete or partial glossectomy and reconstruction with free flaps were grouped according to flap type (ALTFF vs RFFF). Oral functions were assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module, the University of Washington Quality of Life, and the 14-item Oral Health Impact Profile questionnaires at 6 and 12 months after reconstructive surgery.
Results:
Sixty-seven of 80 questionnaires (83.75%) were returned. There were significant differences between the 2 groups concerning the style of resection (P < .005). For all oral function domains, the score improved progressively after the operation (6 and 12 months after the procedure). There were no meaningful differences between the 2 flap types for all oral function domains at 12 months.
Conclusion:
Using the RFFF or ALTFF for reconstruction of tongue defects after cancer resection meaningfully influences oral function. Free flap reconstruction of the tongue is the most critical factor in achieving a successful functional result.
