Long-term effects of a multidisciplinary transition intervention from paediatric to adult care in patients with

Related Experiment Video

Updated: Mar 21, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

1.8K

R P J Geerlings1, A P Aldenkamp2, L M C Gottmer-Welschen1

  • 1Epilepsy Center Kempenhaeghe, Heeze, The Netherlands.

Seizure
|May 1, 2016
PubMed

Insights

Adolescents with epilepsy benefit from multidisciplinary transition clinics, which improve medical and psychosocial outcomes. Patient factors also predict medical improvement, but clinic interventions positively impact overall risk scores.

Area of Science:

  • Neurology
  • Pediatric Epilepsy
  • Transition of Care

Background:

  • Adolescents with epilepsy face unique challenges during healthcare transitions.
  • Understanding factors influencing medical and psychosocial outcomes is crucial for effective care.

Purpose of the Study:

  • To evaluate the long-term effects of a multidisciplinary transition intervention.
  • To compare intervention effects with patient-related intrinsic factors on outcomes.

Main Methods:

  • 114 patients from an Epilepsy Transition Clinic were invited; 66 completed questionnaires.
  • Discriminant analyses assessed predictors of medical and psychosocial outcome improvement.
  • Patient characteristics and risk scores were re-evaluated.

Main Results:

  • Patient-related intrinsic factors strongly predicted medical outcome improvement (72.7%).
  • Transition interventions predicted medical (56.1%) and educational/vocational (53.0%) outcomes.
  • Interventions also improved the overall risk score (54.5%).

Conclusions:

  • Multidisciplinary epilepsy transition clinics likely benefit adolescents.
  • Interventions positively influence medical, educational/vocational outcomes, and risk scores.
  • Overall psychosocial outcomes improved for most patients.
Abstract

Keywords:
EpilepsyPsychosocial outcomeTransition clinicTransition interventionTransition to adult care

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

21.3K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
315
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.6K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
368
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
1.9K
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
312