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Updated: Mar 21, 2026

Mass Production of Entomopathogenic Fungi, Metarhizium robertsii and Metarhizium pinghaense, for Commercial Application Against Insect Pests

Mass Production of Entomopathogenic Fungi, Metarhizium robertsii and Metarhizium pinghaense, for Commercial Application Against Insect Pests

Published on: March 31, 2022

Genetically Engineering Entomopathogenic Fungi.

H Zhao¹, B Lovett², W Fang¹

¹Zhejiang University, Hangzhou, Zhejiang, China.

Advances in Genetics

|May 1, 2016

Summary

This summary is machine-generated.

Genetically engineered entomopathogenic fungi show enhanced virulence and environmental tolerance, offering a sustainable alternative to chemical insecticides for pest control. These improved mycoinsecticides address market limitations and promote eco-friendly agricultural practices.

Keywords:

Antiinsect protein Biological control Entomopathogenic fungi Genetic engineer Mycoinsecticide Vector-borne disease

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Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests

Published on: September 28, 2021

Area of Science:

Agricultural Science
Biotechnology
Entomology

Background:

Mycoinsecticides are eco-friendly alternatives to chemical insecticides but suffer from low virulence and performance inconsistency.
Genetic engineering offers a pathway to enhance fungal virulence and stress tolerance for improved biocontrol efficacy.

Purpose of the Study:

To review advancements in genetically engineering entomopathogenic fungi for enhanced biocontrol applications.
To highlight strategies for improving mycoinsecticide performance and safety.

Main Methods:

Engineering fungi to express insecticidal proteins and overexpressing native genes for enhanced virulence.
Utilizing protein engineering to create novel insecticidal proteins with combined functional domains.
Introducing stress tolerance pathways (photoreactivation, pigment synthesis) and employing gene knockout for specific applications.

Main Results:

Significant improvements in fungal virulence and tolerance to abiotic stresses like UV radiation have been achieved.
Engineered strains exhibit hypervirulence, with gene knockout strategies ensuring limited environmental persistence.
Safety is enhanced through the use of specific effector proteins and removal of selection markers.

Conclusions:

Genetic engineering provides powerful tools to develop highly effective and safe mycoinsecticides.
These advancements offer environmentally sound solutions for managing insect pests, addressing concerns over synthetic chemical insecticides.