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Related Experiment Video

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Initial Outcomes of a Lung Cancer Screening Program in an Integrated Community Health System.

Andrew T Miller1, Patricia Kruger2, Karen Conner3

  • 1Department of Internal Medicine, Intermountain Medical Center, Murray, Utah.

Journal of the American College of Radiology : JACR
|May 2, 2016
PubMed
Summary

Low-dose CT (LDCT) lung cancer screening in a community health system detected early-stage lung cancer at a rate comparable to national trials. This real-world data supports LDCT effectiveness in diverse healthcare settings.

Keywords:
LDCTLung cancer screeninglow-dose CTlung cancerlung nodulespulmonary nodules

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Area of Science:

  • Pulmonology
  • Oncology
  • Radiology

Background:

  • Lung cancer screening with low-dose CT (LDCT) shows reduced mortality.
  • Translating LDCT efficacy to community-based screening effectiveness requires evaluation.

Purpose of the Study:

  • To report baseline patient characteristics and malignancy rates from an integrated community health system's LDCT screening program.
  • To assess the real-world effectiveness of LDCT lung cancer screening.

Main Methods:

  • Screening conducted at 10 community centers within a 22-hospital system (2013-2015).
  • LDCT interpretations by 20 radiologists using structured reporting and a tracking system.
  • Manual chart review for malignancy detection rate calculation.

Main Results:

  • 274 patients enrolled after screening criteria were met.
  • Malignancy detected in 4.0% of enrollees (11/274).
  • 8 lung cancers and 3 extrapulmonary malignancies identified; 3 early-stage lung cancers received therapy.

Conclusions:

  • LDCT screening in an integrated community health system detected early-stage lung cancer.
  • Detection rates were similar to those reported in other lung cancer screening trials.