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Updated: Mar 21, 2026
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Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
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[Narcolepsy in sleepy obese children. Two case reports]
C Rives-Lange1, A Karsenty1, H Chantereau1
1Service de nutrition et gastro-entérologie pédiatriques, hôpital Trousseau, AP-HP, université Paris 6, 26, avenue du Dr-Arnold-Netter, 75012 Paris, France.
Summary
Narcolepsy, a sleep disorder, can cause obesity in children. Early diagnosis and treatment of narcolepsy are crucial for managing both sleep issues and weight gain.
Area of Science:
- Neurology
- Pediatrics
- Sleep Medicine
Background:
- Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, sleep attacks, and cataplexy.
- Hypocretin deficiency in narcolepsy may influence appetite regulation, potentially linking it to obesity and precocious puberty in children.
Observation:
- Two young girls presented with obesity and subsequently developed narcolepsy with rapid weight gain.
- These cases highlight a potential association between narcolepsy and unexplained weight gain in pediatric patients.
Findings:
- Specific medications improved wakefulness and stabilized weight in the observed patients.
- Narcolepsy should be considered in obese children experiencing excessive sleepiness, avoiding misdiagnosis as obstructive sleep apnea.
Implications:
- Prompt diagnosis of narcolepsy in sleepy, obese children is essential.
- Nocturnal polysomnography and multiple sleep latency tests are recommended for accurate diagnosis and treatment initiation.
- Effective treatment can address both narcolepsy symptoms and associated weight gain.
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