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Updated: Mar 21, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Post-traumatic complex regional pain syndrome: clinical features and epidemiology
Chiara Ratti1, Andrea Nordio1, Giuseppina Resmini2
1Orthopaedic, Traumatologic Clinic, University Hospital "Ospedali Riuniti", Trieste, Italy.
Abstract:
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition that occurs after a tissue injury (fractures, sprain, surgery) of the upper or lower extremities. A clear pathophysiological mechanism has not been established yet and different patterns are considered to play a role in the genesis of the disease. The diagnosis is made by different diagnosis criteria and a gold standard has not been established yet. Incidence of CRPS is unclear and large prospective studies on the incidence and prevalence of CRPS are scarce. The aim of this review is to give an overview on the prevalent data regarding this chronic syndrome.
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