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Automated Protocols for Macromolecular Crystallization at the MRC Laboratory of Molecular Biology

Automated Protocols for Macromolecular Crystallization at the MRC Laboratory of Molecular Biology

Published on: January 24, 2018

Macromol. Rapid Commun. 9/2016.

Lan Xie^1,2, Huan Xu^2,3, Zhong-Ming Li²

¹College of Materials and Metallurgy, Guizhou University, Guiyang, 550025, China.

Macromolecular Rapid Communications

|May 3, 2016

Summary

Researchers developed a shish-kebab structure in poly(lactic acid) stereocomplex using shear flow. The crystal structure of the kebab components depended on crystallization temperature.

Keywords:

crystal structures polymorphism stereocomplex poly(lactic acid)transient shear flow

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Area of Science:

Polymer Science
Materials Science

Background:

Poly(lactic acid) stereocomplex (PLA) is a biodegradable polymer with tunable properties.
Controlling the morphology of PLA stereocomplex is crucial for advanced applications.

Purpose of the Study:

To investigate the formation of shish-kebab superstructure in poly(lactic acid) stereocomplex.
To understand the influence of transient shear flow on the self-assembly of stereocomplex chains.
To analyze the effect of crystallization temperature on the morphology of the kebab structures.

Main Methods:

Utilizing transient and strong shear flow to induce alignment of poly(lactic acid) stereocomplex chains.
Employing microscopy techniques to observe the developed shish-kebab superstructure.
Varying crystallization temperatures to study their impact on the lateral kebab crystal formation.

Main Results:

A distinct shish-kebab superstructure was successfully developed in poly(lactic acid) stereocomplex under shear flow.
Shear-aligned stereocomplex chains preferentially formed the central shish component.
The crystal form of the lateral kebab structures exhibited a significant dependence on the crystallization temperature.

Conclusions:

Transient shear flow is an effective method for creating ordered shish-kebab structures in poly(lactic acid) stereocomplex.
The crystallization temperature is a critical parameter controlling the morphology of the kebab components in this superstructure.
This study provides insights into the structure-property relationships of poly(lactic acid) stereocomplex materials.