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Related Experiment Video

Updated: Mar 21, 2026

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
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Integrating Electronics and Microfluidics on Paper.

Mahiar M Hamedi1, Alar Ainla1, Firat Güder1

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA.

Advanced Materials (Deerfield Beach, Fla.)
|May 3, 2016
PubMed
Summary

Researchers demonstrate monolithic integration of paper microfluidics and printed electronics. This breakthrough enables the fabrication of complex 2D and 3D devices with fluidic and electrical functionalities on a single paper substrate.

Keywords:
diagnosticselectroanalytical devicesorganic electronicspaper microfluidicsprinted electronics

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Last Updated: Mar 21, 2026

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Published on: April 1, 2016

8.1K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
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Area of Science:

  • Materials Science
  • Electrical Engineering
  • Fluidics

Background:

  • Paper microfluidics and printed electronics have historically developed as separate fields.
  • Existing methods face challenges in integrating these two technologies due to material and processing incompatibilities.

Purpose of the Study:

  • To demonstrate the monolithic integration of microfluidics and electronics on a paper substrate.
  • To enable the fabrication of advanced paper-based devices combining fluidic and electronic functionalities.

Main Methods:

  • Development of a novel integration technique for paper microfluidics and printed electronics.
  • Printing of 2D and 3D fluidic, electrofluidic, and electrical components directly onto paper.

Main Results:

  • Successful monolithic integration of microfluidic and electronic components on paper.
  • Demonstration of printing capabilities for both 2D and 3D fluidic and electrical structures.
  • Fabrication of functional devices utilizing the integrated paper platform.

Conclusions:

  • Monolithic integration of microfluidics and electronics on paper is achievable.
  • This approach facilitates the creation of versatile paper-based devices with combined functionalities.
  • Opens new avenues for low-cost, disposable, and portable electronic and microfluidic systems.