Related Experiment Video
Updated: Mar 21, 2026

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
Published on: November 22, 2024
Relationship between mean platelet volume, platelet distribution width, plateletcrit and varicocele
H Polat1, M T Gulpinar2, M A Sarıca3
1Department of Urology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey.
This study found no significant differences in platelet count or platelet indices between men with and without varicocele. Varicocele did not correlate with these specific platelet markers in the studied population.
Area of Science:
- Hematology
- Urology
- Vascular Biology
Background:
- Platelet count and indices (MPV, RDW, PCT) are altered in various pathologies.
- Varicocele is a vascular disease with an unclear etiology.
- Understanding potential systemic markers associated with varicocele is important.
Purpose of the Study:
- To investigate the relationship between varicocele and platelet count.
- To analyze specific platelet indices (MPV, PDW, PCT) in varicocele patients.
- To compare platelet parameters between varicocele patients and controls.
Main Methods:
- Cross-sectional study comparing 69 varicocele patients with 56 controls.
- Analysis of platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT).
- Evaluation of semen parameters in both groups.
Main Results:
- Semen abnormalities were more frequent in the varicocele group (53.6%) compared to controls (33.9%) (P < 0.05).
- No statistically significant differences were observed in platelet count, MPV, PDW, or PCT between varicocele patients and controls.
- Platelet parameters did not show a significant association with the presence of varicocele.
Conclusions:
- The presence of varicocele is not associated with significant alterations in platelet count or common platelet indices.
- While varicocele is linked to higher rates of semen abnormalities, it does not appear to affect systemic platelet markers.
- Further research may explore other potential systemic inflammatory or vascular markers in varicocele.
Related Concept Videos
Varicose Veins I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Esophageal Varices-I: Introduction
Formation of the Platelet Plug
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...

