Clinical Characteristics of Sphenoid Sinus Fungal Ball Patients With Visual Disturbance

Jong Sei Kim1, Byung Kil Kim1, Sang Duk Hong1

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Insights

Sphenoid sinus fungal balls can cause vision loss, especially in older women. A sphenoid sinus wall defect is a key risk factor for visual disturbance, necessitating early surgical intervention.

Area of Science:

  • Otolaryngology
  • Ophthalmology
  • Radiology

Background:

  • Sphenoid sinus fungal balls are rare, often asymptomatic, but can lead to irreversible visual disturbances.
  • Visual impairment in these cases has a poor prognosis, highlighting the need for early detection and intervention.

Purpose of the Study:

  • To investigate the clinical features of patients diagnosed with sphenoid sinus fungal balls.
  • To identify factors associated with the development of visual disturbances in affected individuals.

Main Methods:

  • Retrospective review of medical records for 47 patients who underwent endoscopic sinus surgery for sphenoid sinus fungal balls.
  • Comparison of clinical characteristics between patients with and without visual disturbances.

Main Results:

  • A female predominance and older age were observed in the patient cohort.
  • Nasal symptoms were most prevalent. Eight patients experienced visual disturbances.
  • Univariate analysis linked older age, diabetes mellitus, and sphenoid sinus wall defects to visual disturbances. Multivariate analysis confirmed sphenoid sinus wall defects as a significant independent risk factor.

Conclusions:

  • Preventing visual complications is crucial for patients with sphenoid sinus fungal balls.
  • Early surgical treatment is recommended, particularly for patients presenting with a sphenoid sinus wall defect, to mitigate risks.

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