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Clinical Characteristics of Sphenoid Sinus Fungal Ball Patients With Visual Disturbance
Jong Sei Kim1, Byung Kil Kim1, Sang Duk Hong1
1Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Objectives:
A sphenoid sinus fungal ball is a rare disease that can cause visual disturbances. Most afflicted patients remain in an indolent state. However, once the visual disturbance has occurred, the recovery rate is very low. The purpose of this study was to overview the clinical characteristics of patients with a sphenoid sinus fungal ball and ascertain factors possibly related to the occurrence of a visual disturbance.
Methods:
We retrospectively reviewed the medical records of all patients who underwent endoscopic sinus surgery for a sphenoid sinus fungal ball at our hospital. We enrolled 47 patients in this study.
Results:
Old age and a female predominance were noted. Nasal symptoms were the most common symptom. Eight patients showed visual disturbances. We also compared the clinical characteristics between patients with and without visual disturbances in univariate analysis. Old age, underlying diabetes mellitus, and a sphenoid sinus wall defect visible by computed tomography were factors significantly related to the occurrence of visual disturbances. But only sphenoid sinus wall defect showed significance in multivariate analysis.
Conclusion:
It is important to prevent complications, such as visual disturbance, in patients with a sphenoid sinus fungal ball. This study describes an early surgical treatment that may be required for patients with a sphenoid sinus fungal ball and particularly patients with a sphenoid sinus wall defect.
Insights
Sphenoid sinus fungal balls can cause vision loss, especially in older women. A sphenoid sinus wall defect is a key risk factor for visual disturbance, necessitating early surgical intervention.
Area of Science:
- Otolaryngology
- Ophthalmology
- Radiology
Background:
- Sphenoid sinus fungal balls are rare, often asymptomatic, but can lead to irreversible visual disturbances.
- Visual impairment in these cases has a poor prognosis, highlighting the need for early detection and intervention.
Purpose of the Study:
- To investigate the clinical features of patients diagnosed with sphenoid sinus fungal balls.
- To identify factors associated with the development of visual disturbances in affected individuals.
Main Methods:
- Retrospective review of medical records for 47 patients who underwent endoscopic sinus surgery for sphenoid sinus fungal balls.
- Comparison of clinical characteristics between patients with and without visual disturbances.
Main Results:
- A female predominance and older age were observed in the patient cohort.
- Nasal symptoms were most prevalent. Eight patients experienced visual disturbances.
- Univariate analysis linked older age, diabetes mellitus, and sphenoid sinus wall defects to visual disturbances. Multivariate analysis confirmed sphenoid sinus wall defects as a significant independent risk factor.
Conclusions:
- Preventing visual complications is crucial for patients with sphenoid sinus fungal balls.
- Early surgical treatment is recommended, particularly for patients presenting with a sphenoid sinus wall defect, to mitigate risks.
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The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...

