Related Experiment Video
Updated: Mar 21, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii
Zhang-Hua Sun1,2, Ning-Hua Tan3, Guang-Zhi Zeng4
1Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming 650223, China. sunzh@gdim.cn.
Abstract:
Chemical investigation of the 90% acetone extract of the branches and leaves of Sabina gaussenii led to the isolation of two new cinnamyl isovalerate derivatives (1-2) and eighteen known compounds (3-20). Their structures were determined mainly by means of MS, 1D- and 2D-NMR data, and this is the first time these compounds have been reported from this plant. The biological activity test results indicated that the 90% acetone extract showed cytotoxicity against the human lung adenocarcinoma (A549) cell line (IC50 = 0.98 ± 0.1 μg/mL), compound 6 showed cytotoxicities against human cervical carcinoma (HeLa) (IC50 = 0.4 ± 0.1 μM ) and human gastric carcinoma (BGC-823) (IC50 = 0.9 ± 0.2 μM) cancer cell lines, and compound 19 showed cytotoxicities against HeLa (IC50 = 1.5 ± 0.4 μM), BGC-823 (IC50 = 7.0 ± 0.8 μM ), and A549 (IC50 = 10.6 ± 1.5 μM ) cancer cell lines.
More Related Videos
07:13Quantification of Violacein in Chromobacterium violaceum and Its Inhibition by Bioactive Compounds
Published on: August 8, 2025
06:31Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
Published on: November 27, 2015
Related Concept Videos
Aromatic Compounds: Overview
In 1825, Faraday isolated...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Stereoisomerism of Cyclic Compounds
Nonenolizable Aldehydes to Acids and Alcohols: The Cannizzaro Reaction
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions