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Reflections of low calcium epileptiform activity from area CA1 into dentate gyrus in the rat hippocampal slice
D Albrecht1, G Rausche, U Heinemann
1Institut für Physiologie und Pathophysiologie, Universität zu Köln, Cologne, F.R.G.
Brain Research
|February 20, 1989
Abstract:
Lowering of [Ca2+]o induces epileptiform activity in hippocampal area CA1, characterized by slow negative field potentials with superimposed trains of population spikes and by rises in [K+]o. In dentate gyrus slow positive field potentials occur simultaneously with the activity in area CA1. The accompanying small rises in [K+]o may stem from spatial K+ redistribution through glial cells from area CA1.