Related Experiment Video
Updated: Mar 21, 2026

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
Published on: May 26, 2023
[Localization of scotomas in AMD by reading test : Random series of words in standardized format]
W Eisenbarth1, U Pado2, S Schriever3
1Hochschule München, Lothstr. 34, 80335, München, Deutschland. werner.eisenbarth@hm.edu.
Background:
Reading performance that can be measured by reading tests depends on whether reading material with or without contextual continuity is used.
Objective:
The goal of this study was to create a German version of the SKread test and to evaluate it in a clinical setting.
Material And Methods:
The evaluation of the SKread test was first performed on two groups of visually healthy subjects of different ages: a junior group of 25 persons with ages between 20 and 30 years (mean = 25.84 years, SD ± 2.41 years) and a senior group of 25 persons with ages between 51 and 84 years (mean = 62.40 ± 8.46 years). The same measurements were also performed on a group of 18 patients with age-related macular degeneration (AMD) with ages between 75 and 95 years (mean = 81.89 ± 5.48 years). The reading performance was also measured using Radner charts.
Results:
Using reading material without syntactic continuity considerably slowed down the reading speed and increased the error rate. Median reading rates of 11.53 characters/s (CPS) for the junior group and 8.96 CPS for the senior group were clearly lower than those for the Radner charts (22.02 CPS and 18.48 CPS, respectively). In the AMD patients, a statistical analysis of the error rates showed a highly significant difference between the Radner charts and the SKread test (p = 0.00014). Furthermore, by analyzing the errors made in the SKread test information could be obtained about the position of central scotomas. The test-retest reliability of the SKread was very good.
Conclusion:
Information about the position of a central scotoma can be acquired by using the SKread test and an analysis of reading errors, which can augment effective clinical monitoring in AMD and subsequent visual rehabilitation.
More Related Videos
07:12Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
Published on: April 11, 2025
10:14Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023