[Immunohistochemical classification of hypophyseal adenomas]

Immunohistochemical analysis showed production of hormones in more than half of 88 pituitary adenomas that were classified mostly as chromophobe in basic staining during 3 years. Prolactin was the most often detected. A combined production of hormones especially of prolactin and growth hormone was not exceptional. Using a sensitive double indirect immunoperoxidase technique enables economy in spending primary antibodies. Evaluation of hormonal production is important for selection of therapy, as well as for settlement of prognosis.