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Synteny and Evolution02:31

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Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Statistical evidence for common ancestry: Application to primates.

David A Baum1, Cécile Ané2,3, Bret Larget2,3

  • 1Department of Botany, University of Wisconsin, 430 Lincoln Drive, Madison, Wisconsin, 53706. dbaum@wisc.edu.

Evolution; International Journal of Organic Evolution
|May 4, 2016
PubMed
Summary

This study quantifies evidence for common ancestry (CA) in primates using statistical methods. Results overwhelmingly reject separate ancestry (SA) hypotheses, strongly supporting primate CA.

Keywords:
Biogeographyfossilspermutation tail probabilityphylogenetic autocorrelationseparate ancestrytree agreement

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Area of Science:

  • Evolutionary biology
  • Phylogenetics
  • Biostatistics

Background:

  • The theory of descent from common ancestry (CA) is well-supported by qualitative evidence.
  • Formal methods are needed to quantify the evidential support for CA over separate ancestry (SA).

Purpose of the Study:

  • To explore statistical methods for quantifying evidential support for CA in primates.
  • To test species SA and family SA hypotheses against CA.

Main Methods:

  • Implemented statistical tests using morphological, molecular, and biogeographic data.
  • Developed new methods for phylogenetic autocorrelation and analysis of fossil taxa.
  • Focused on primate data to test CA against species and family SA.

Main Results:

  • Overwhelmingly rejected both species SA and family SA hypotheses with infinitesimal P values.
  • Found tremendously strong statistical support for the common ancestry of all primates.
  • Demonstrated the utility of statistical testing for historical hypotheses.

Conclusions:

  • Statistical quantification strongly supports the common ancestry of primates.
  • The developed methods provide robust tools for testing evolutionary hypotheses.
  • Future research should continue to refine statistical approaches in evolutionary biology.