Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Determinants of axial length growth in infantile persistent fetal vasculature following early lensectomy-vitrectomy: a retrospective cohort.

BMC ophthalmology·2026

Same author

Impact of ambient fine particulate matter (PM<sub>2.5</sub>) pollution on disease burden in BRICS from 1990 to 2023: evidence from the Global Burden of Disease Study 2023.

BMJ global health·2026

Same author

Multilevel Proteome Analysis Reveals the Region-specific Components of the Human Milk Fat Globule Membrane in China.

Journal of agricultural and food chemistry·2026

Same author

Accelerated sagittal remodeling of lumbar facet joints following L4-L5 posterior lumbar interbody fusion: a longitudinal MRI study.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026

Same author

Dynamic low-saturated structural colors empowered by a metasurface with symmetry-protected quasi-bound states in the continuum.

Optics letters·2026

Same author

The AtMYB2 downstream targets AtMYB48 and AtbHLH68 redundantly regulate cambial cell proliferation and xylem differentiation in Arabidopsis thaliana.

Plant communications·2026

Search research articles

Related Experiment Video

Updated: Mar 21, 2026

Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents

Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents

Published on: May 1, 2012

Guided Bloch surface wave resonance for biosensor designs.

Xiu-Bao Kang, Lan-Jun Liu, Hai Lu

Journal of the Optical Society of America. A, Optics, Image Science, and Vision

|May 4, 2016

Summary

A novel guided Bloch surface wave resonance (GBR) configuration enhances label-free biosensing. This method uses photonic crystals for high-quality, sensitive biosensors with compact designs.

More Related Videos

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Published on: February 10, 2014

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Related Experiment Videos

Last Updated: Mar 21, 2026

Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents

Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents

Published on: May 1, 2012

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Published on: February 10, 2014

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Area of Science:

Photonics
Nanotechnology
Biomedical Engineering

Background:

Label-free biosensing is crucial for real-time monitoring of biological interactions.
Existing biosensing technologies face limitations in sensitivity, quality, and design flexibility.
Bloch surface waves (BSWs) offer potential for enhanced sensing due to strong field confinement.

Purpose of the Study:

To introduce a guided Bloch surface wave resonance (GBR) configuration for advanced label-free biosensing.
To leverage subwavelength gratings and 1D photonic crystals for improved BSW characteristics.
To demonstrate the suitability of GBR for developing high-figure-of-merit biosensors.

Main Methods:

Realization of GBR by coupling diffracted light from a subwavelength grating with BSWs.
Utilizing a 1D photonic crystal slab at the interface between the grating and bio-solution.
Characterization of resonance spectrum, focusing on quality factor and sideband transmission.

Main Results:

The GBR configuration successfully sustains the Bloch surface mode.
Photonic crystals enabled simultaneous enhancement of resonance quality and reduction of sideband transmissions.
High sensitivity was achieved due to strong overlap between the BSW mode and the bio-solution.

Conclusions:

The GBR configuration provides a promising platform for label-free biosensing.
The design offers high quality, low sideband transmission, and excellent sensitivity.
Compact, high-figure-of-merit biosensors can be realized using this GBR approach.