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Updated: Mar 21, 2026

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
Published on: September 20, 2018
Intestinal Behçet's disease with pyoderma gangrenosum successfully treated with the combination therapy of adalimumab
Yusuke Kashiwado1, Ayumi Uchino1, Toshiyuki Ota1
1a Department of Rheumatology , Aso Iizuka Hospital , Fukuoka , Japan.
Abstract:
A 24-year-old male presented with orogenital ulcers, folliculitis, and progressive painful skin ulcers with a raised inflammatory border. Colonoscopy revealed volcano-shaped intestinal ulcers in the ascending colon, and hence, he was diagnosed as intestinal Behçets disease (BD) with pyoderma gangrenosum (PG). Treatment with systemic glucocorticoids and adalimumab dramatically improved the patient's symptoms. Our case demonstrates that early induction of adalimumab may contribute to the successful treatment of such difficult-to-treat conditions as intestinal BD with PG.
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