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Updated: Mar 21, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
[Endoscopic full-thickness resection of colorectal polyps]
Laurie Hageman1, Jolanda Strebus, Bas W van der Spek
1Noordwest Ziekenhuisgroep, locatie Alkmaar, afd. Maag-, Darm-, Leverziekten, Alkmaar.
Endoscopic full-thickness resection (eFTR) offers a minimally invasive alternative for removing colorectal neoplasias when standard endoscopic methods fail. Promising initial results suggest eFTR may be a viable option, warranting further comparative studies.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- National screening programs increase detection of colorectal neoplasias, including T1-carcinomas.
- Standard endoscopic resection techniques are often insufficient for certain lesions.
Purpose of the Study:
- To evaluate endoscopic full-thickness resection (eFTR) as an alternative to surgery for specific colorectal neoplasias.
- To assess the potential of eFTR for difficult-to-resect adenomas and T1-carcinomas.
Main Methods:
- Review of initial research on endoscopic full-thickness resection (eFTR).
- Focus on applications in non-lifting adenomas, difficult-to-reach adenomas, and T1-carcinomas.
Main Results:
- Endoscopic full-thickness resection (eFTR) shows promising initial outcomes.
- eFTR is presented as a minimally invasive alternative to surgical resection.
Conclusions:
- Endoscopic full-thickness resection (eFTR) is a promising technique for specific colorectal neoplasias.
- Further prospective studies are needed to compare eFTR efficacy and safety against surgical resection.
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