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A close relationship between microvilli and metabolic cooperation deficiency in embryonal carcinoma cells
I F Purcell1, T A Smith, C E Patek
1Department of Pathology, University Medical School, Edinburgh, Scotland.
Experimental Cell Research
|May 1, 1989
Abstract:
A revertant clone has been isolated from the metabolic cooperation-deficient embryonal carcinoma clone PT2md1. In PT2md1, its cooperation-competent parent, and its cooperation-competent revertant an inverse correlation has been demonstrated between cooperation competence and the incidence of microvilli. This demonstration, together with a similar correlation previously reported in an independently isolated series of cell lines, establishes a close causal relationship between the incidence of microvilli and communication deficiency.