Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Necrosis01:16

Necrosis

7.2K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
7.2K
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

10
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
10
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

2.2K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.2K
Gallbladder01:17

Gallbladder

2.8K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
2.8K
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.7K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.7K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.4K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ConLymphNet: A Generalizable Region-Constrained Deep Learning Architecture for Precise Abdominal Lymph Node Segmentation Across Cancer Types.

JCO clinical cancer informatics·2026
Same author

Pancreaticoduodenectomy without venous reconstruction in locally advanced pancreatic cancer with non-reconstructible mesenteric venous anatomy: Role of collateral circulation.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2026
Same author

Role of Dynamic Perfusion CT in Pancreatic Adenocarcinoma.

The Indian journal of radiology & imaging·2026
Same author

Artificial Intelligence for Molecular Subtyping in Unresectable Gallbladder Cancer: A Proof-of-Concept Study for CT-based HER2 Status Prediction.

Journal of clinical and experimental hepatology·2026
Same author

Management of multiple common bile duct stones via laparoscopic transcholedochal exploration: an observational study.

Frontiers in surgery·2026
Same author

Top-down versus step-up approach after endoscopic ultrasound-guided drainage of infected walled-off necrosis: a randomized controlled trial.

Endoscopy·2026

Related Experiment Videos

Necrotizing Soft Tissue Infection Caused by Spilled Gallstones.

Narendra Pandit1, Harjeet Singh2, Hemanth Kumar1

  • 1Division of Surgical Gastroenterology, Department of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

ACG Case Reports Journal
|May 5, 2016
PubMed
Summary

Gallstones spilled during gallbladder surgery can rarely cause severe abdominal wall infections. This case highlights a serious complication of cholecystectomy, emphasizing the need for careful surgical technique.

Related Experiment Videos

Area of Science:

  • Surgical Case Report
  • Infectious Disease
  • Gastrointestinal Surgery

Background:

  • Cholecystectomy is a common surgical procedure for gallbladder disease.
  • Gallstone spillage during cholecystectomy is a known complication.
  • Necrotizing soft tissue infections are severe bacterial infections.

Observation:

  • A 57-year-old woman developed a necrotizing abdominal wall infection one year post-cholecystectomy.
  • Surgical exploration revealed pigmented gallstones and pus in the abdominal wall and gallbladder fossa.
  • The infection was linked to intraoperative gallstone spillage.

Findings:

  • Intraoperative gallstone spillage, though common, can lead to rare but severe complications.
  • Necrotizing soft tissue infection of the abdominal wall is a potential sequela.
  • Prompt surgical intervention is crucial for managing such infections.

Implications:

  • Highlights the importance of meticulous surgical technique during cholecystectomy to minimize gallstone spillage.
  • Underscores the potential for delayed, serious infectious complications following gallbladder surgery.
  • Suggests vigilance for atypical presentations of infection in patients with a history of cholecystectomy.