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Osteopenic features of the hip joint in patients with cerebral palsy: a hospital-based study
Sang Young Moon1, Soon-Sun Kwon2, Byung Chae Cho3
1Department of Orthopaedic Surgery, Yeol Lin Hospital, Kyungki, South Korea.
Insights
Bone mineral density in children with cerebral palsy (CP) is significantly lower, especially in those with severe hip instability or higher Gross Motor Function Classification System (GMFCS) levels. This impacts hip joint health.
Area of Science:
- Orthopedics
- Pediatric Radiology
- Neurology
Background:
- Cerebral palsy (CP) can affect bone development and density.
- Hip joint complications are common in children with CP.
- Assessing bone mineral density is crucial for managing CP-related orthopedic issues.
Purpose of the Study:
- To evaluate hip joint bone mineral density in pediatric patients with cerebral palsy (CP).
- To determine the correlation between bone density, hip instability, and motor function in CP.
- To identify factors influencing bone attenuation in the hip joint of children with CP.
Main Methods:
- Computed tomography (CT) scans of the hip joint were analyzed in 126 children with CP and 86 controls.
- Bone attenuation (Hounsfield units) of the acetabulum and femur was measured.
- Adjustments were made for hip instability (migration percentage) and Gross Motor Function Classification System (GMFCS) levels.
Main Results:
- Children with CP exhibited significantly lower bone attenuation in the acetabulum and femur compared to controls.
- Lower bone attenuation was strongly associated with higher GMFCS levels (IV and V) and increased hip migration percentage (>37%).
- Bone attenuation decreased notably with increasing severity of hip instability and motor impairment.
Conclusions:
- Hip joint bone mineral density is significantly reduced in children with cerebral palsy.
- Both the severity of hip instability and the GMFCS level are critical determinants of bone attenuation in the hip.
- These findings highlight the need for targeted interventions to address bone health in pediatric CP patients.
Aim:
We aimed to evaluate the bone mineral density of the hip joint in patients with cerebral palsy (CP).
Method:
Patients with CP younger than 18 years who underwent three-dimensional hip examination by computed tomography were analysed. Bone attenuation of the acetabulum and femur was measured as Hounsfield units (HU), and was adjusted for affecting factors such as hip instability and Gross Motor Function Classification System (GMFCS).
Results:
One hundred and twenty-six patients with CP and 86 typically developing participants were included. The average bone attenuation was significantly lower in those with CP than in the comparison group (acetabulum: 70.8HU, 95% confidence interval [95% CI] 59.9-81.8; femur: 82.2HU, 95% CI 70.4-95.8). Compared with GMFCS levels I to III, bone attenuation was significantly lower for GMFCS levels IV (acetabulum: 30.9HU, 95% CI 15.7-46.2; femur: 39.7HU, 95% CI 19.9-59.5) and V (acetabulum: 51.7HU, 95% CI 35.9-67.5; femur: 72.5HU, 95% CI 51.9-93.0). The average bone attenuation decreased when the migration percentage was over 37% (acetabulum: 11.6HU, 95% CI 1.4-24.6; femur: 26.8HU, 95% CI 9.9-43.6).
Interpretation:
Bone attenuation of the acetabulum and femur was significantly affected both by GMFCS level and by severity of hip instability.
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