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Updated: Mar 21, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
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[Immunosuppression after corneal transplantation : Clinical standards and novel approaches]

K Wacker1, T Reinhard2

  • 1Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg im Breisgau, Deutschland. katrin.wacker@uniklinik-freiburg.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|May 6, 2016
PubMed

Corticosteroid eye drops are the mainstay of immunosuppressive therapy after routine lamellar and perforating corneal transplantation. Commonly occurring side effects are cataract formation and increased intraocular pressure. Alternative immunosuppressive agents could allow the dosage of glucocorticoids to be reduced. The antibiotic azithromycin is a candidate drug that showed anti-inflammatory properties in cell cultures and animal models and has positive effects on transplant rejection.

Keywords:
Anti-inflammatory agentsAzithromycinCorneal transplantationGlucocorticoidsGraft rejection

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