Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Brain tumors in infants].

J N Guilburd, C Lapras, J Guyotat

    Harefuah
    |February 1, 1989
    PubMed
    Summary

    Pediatric brain tumor surgery offers a 46% survival rate, with radical excision leading to good functional recovery. However, infant brain irradiation often causes severe handicaps, making surgery the preferred treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    5-ALA induced PpIX fluorescence spectroscopy in neurosurgery: a review.

    Frontiers in neuroscience·2024
    Same author

    Cerebral empyema and abscesses due to Cutibacterium acnes.

    Medecine et maladies infectieuses·2019
    Same author

    Combined analysis of MGMT methylation and dynamic-susceptibility-contrast MRI for the distinction between early and pseudo-progression in glioblastoma patients.

    Revue neurologique·2019
    Same author

    Spectral complexity of 5-ALA induced PpIX fluorescence in guided surgery: a clinical study towards the discrimination of healthy tissue and margin boundaries in high and low grade gliomas.

    Biomedical optics express·2019
    Same author

    Optimization of high-grade glioma resection using 5-ALA fluorescence-guided surgery: A literature review and practical recommendations from the neuro-oncology club of the French society of neurosurgery.

    Neuro-Chirurgie·2019
    Same author

    Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.

    Neuro-Chirurgie·2017

    Area of Science:

    • Pediatric neurosurgery
    • Pediatric oncology
    • Neuroscience

    Context:

    • Intracranial tumors in infants present unique challenges for treatment and long-term outcomes.
    • A 15-year study analyzed outcomes for children with early-onset brain tumors.

    Purpose:

    • To evaluate the efficacy of surgical management versus radiotherapy for pediatric intracranial tumors presenting in infancy.
    • To assess survival rates and long-term neurodevelopmental outcomes in this patient cohort.

    Summary:

    • Surgical outcomes for 76 children with intracranial tumors diagnosed in infancy were reviewed.
    • Complete or subtotal tumor removal correlated with higher survival (46%) and favorable neuropsychological status.
    • Brain irradiation in infants resulted in severe handicaps, indicating its limited role except for highly malignant or incompletely resected tumors.

    Impact:

    • Radical surgery provides the best chance for survival and good functional recovery in infants with brain tumors.
    • Findings suggest a paradigm shift towards prioritizing surgical intervention over radiotherapy in this age group.
    • Highlights the detrimental effects of irradiation on the developing infant brain, emphasizing conservative use of radiotherapy.

    Related Experiment Videos