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Differential associative behaviour of mitotic and meiotic acrocentric chromosomes
M C Dumont1, M J Bello, M R Guichaoua
1Department of Embryology and Cytogenetics, Faculty of Medicine, Marseille, France.
Human Genetics
|April 1, 1989
Abstract:
A comparative study of the association of mitotic acrocentric chromosomes and acrocentric bivalents at the pachytene stage shows that at least two factors can act in the associative behaviour of these chromosomes: (1) Nor activity and (2) the presence of satellite DNA in the short arms of these chromosomes. These factors do not act with the same intensity in the two cell lines studied. In lymphocytes, Nor activity prevails, whereas satellite DNA plays the main role in the association of acrocentric chromosomes in germ cells at the pachytene stage.