The Mid-Term Changes of Pulmonary Function Tests After Phrenic Nerve Transfer
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Updated: Mar 21, 2026

Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Published on: May 25, 2015
Masoud Yavari1, Seyed Esmail Hassanpour2, Mohammad Khodayari1
1Department of Reconstructive Surgery, Shahid Behesti University of Medical Sciences, Tehran, IR Iran.
Background:
In the restoration of elbow flexion, the phrenic nerve has proven to be a good donor, but considering the role of the phrenic nerve in respiratory function, we cannot disregard the potential dangers of this method.
Objectives:
In the current study, we reviewed the results of pulmonary function tests (PFT) in four patients who underwent phrenic nerve transfer.
Patients And Methods:
We reviewed the results of serial spirometry tests, which were performed before and after phrenic nerve transfer surgery.
Results:
All patients regained Biceps power to M3 strength or above. None of our patients experienced pulmonary problems or respiratory complaints, but a significant reduction of spirometric parameters occurred after surgery.
Conclusions:
This study highlights the close link between the role of the phrenic nerve and pulmonary function, such that the use of this nerve as a transfer donor leads to spirometric impairments.
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