[Anaphylactic shock following administration of an infusion solution containing fructose?]

A sixty-seven year old female patient who received post-operatively an i.v. infusion of Sterofundin I, suffered an anaphylactic shock with cyanosis, dyspnoea and progressive hypotension. Over a period of 90 min there were ECG changes similar to acute posterior myocardial infarction and arrhythmias (total AV-block with high compensative rate). This could be due to circulatory shock but more probably to a transitory coronary spasm. Clinical signs and symptoms exclude a hereditary fructose intolerance because of case history and blood results as well as complications described in the literature due to low dosage of fructose. An intracutaneous test confirmed a hypersensitivity of fructose-containing i.v. infusion.