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Estrogens and the pathophysiology of Parkinson's disease
1Department of Neurology, University of Arizona, Tucson 85724.
The International Journal of Neuroscience
|March 1, 1989
Abstract:
Two postmenopausal female Parkinsonian patients experienced exacerbation of symptoms including levodopa-induced "On-Off" following withdrawal or reduction of conjugated estrogen therapy. This report supports animal data implicating female sexual hormones in the pathophysiology of Parkinson's disease and levodopa-induced dyskinesias.